Date of Award
Master of Science in Vision Science
Salisa K. Williams
Purpose: Scanning laser polarimetry using the GDxVCC was conducted on diabetic and non-diabetic subjects to determine if RNFL (retinal nerve fiber layer) thickness differed between these two cohort groups. Design: Prospective, comparative case series, pilot study Subjects: Forty-four diabetic and forty-two non-diabetic subjects.
Methods: Subjects had a one-time office visit, consisting of visual acuities, pupil assessment, angle assessment, intraocular pressures, a GDxVCC scan, and a full fundus exam to determine if there were clinical findings of retinopathy present. Retinopathy was staged using the ETDRS (Early Treatment Diabetic Retinopathy Study) protocol.
Conclusion: The RNFL (retinal nerve fiber layer) in diabetic subjects was found to be statistically significantly thinner than the RNFL in non-diabetic subjects, but additional data collection is needed before conclusive results can be obtained.
Sezer, Mary E.; Wilson, Tawnya; Porter, Lisa Lin; and Rioux, Nichole P., "Evaluating nerve fiber layer changes in diabetic subjects using the GDxVCC" (2005). College of Optometry. 1524.