Date of Award


Degree Type


Degree Name

Master of Science in Vision Science

Committee Chair

Diane P. Yolton


This study compared the Lactoplate Immunoassay Test, which assessed tear lactoferrin concentrations, and standard clinical methods for the diagnosis of dry eye. Thirty subjects were divided into three groups:control, questionable and dry eye using the standard clinical tests of tear break-up time, rose bengal staining and the presence of specific symptoms. The tear lactoferrin concentration was also measured in all of the subjects. The lactoferrin concentration was not significantly different between the groups. Therefore, tear lactoferrin alone is not a sensitive diagnostic aid for this population of dry eye subjects. However, it is a good screening tool to be used in addition to standard clinical diagnostic methods.

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