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Date of Graduation
Capstone Project (On-Campus Access Only)
Master of Science in Physician Assistant Studies
Judy Ortiz, PA-C, MS
Objective: Due to the toxic nature and increasing resistance of pediculicidal agents in the treatment of head lice, a new, safe, effective treatment is needed. This study uses a silicone-based, Pre-Combing Conditioner to treat pediculosis and looks at its overall effectiveness and subject-ta-subject variability. Success is defined as the absence of live head lice at day 14, following two uses of the Pre-Combing Conditioner.
Methods: Single blind, repeated measures study enrolling 59 subjects ages 2 to 18 years. Results: Fifty-eight of the subjects (98%) completed the study. Primary efficacy, defined as number of live head lice on day 14, was 100%. The percentage of subjects with live lice on day 7 was 14%. The estimated number of nits before and after treatments did not change significantly.
Conclusion: The Pre-Combing Conditioner is a safe, effective treatment for head lice. The fact that most or all nits remained after two treatments may be a misleading negative outcome of this study: the incubation period for the nit is 7 to 10 days. Of the 86% of patients on day 7 who had no lice, it can be assumed that by day 14, which was 14 days from the original treatment, the nits were no longer viable.
Larrabee, Angela M., "Pilot study: Lice and nit removal regimen with pre-combing conditioner effectiveness evaluation" (2002). School of Physician Assistant Studies. 366.