Date of Graduation

Summer 8-12-2017

Degree Type

Capstone Project

Degree Name

Master of Science in Physician Assistant Studies


Background: Diabetes mellitus type 2 affects millions of people across the world. The problem is only increasing. In addition to medications, most interventions have focused on diet and exercise, and these regimens prove difficult to many patients. Recent data has shown that sedentary behavior can have negative effects on overall health in healthy and diabetic patients alike. This systematic review focuses on the benefit to waist circumference (WC) and body mass index (BMI) by breaking up long bouts of sedentary time.

Methods: An exhaustive medical literature search was conducted using MEDLINE-Ovid, CINAHL, and Web of Science using the keywords: diabetes mellitus type 2, sedentary lifestyle, and motor activity.

Results: The two studies that met inclusion criteria show that prolonged sedentary behaviors in adults with DMT2 had significant associations with increased WC and BMI. Both studies used isotemoral substitution analysis to correlate a decrease in BMI and WC when prolonged sitting time was replaced with shorter bouts of sitting time.

Conclusion: While moderate to vigorous activity remains one of the best interventions for adults with DMT2 in controlling WC and BMI, this patient population can benefit with a simple intervention of reducing prolonged sedentary activity to no more than 30 minutes at a time.

Keywords: Diabetes mellitus type 2, physical activity, and sedentary lifestyle.