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Date of Award
Dissertation (On-Campus Access Only)
Doctor of Psychology (PsyD)
Michael Daniel, PsyD
Objective: The goal of this research was to determine the influence of vascular burden on both neurocognitive and instrumental functioning in individuals with Parkinson’s disease.
Methods: Archival data for 418 participants from the National Alzheimer’s Coordinating Center Uniform Data Set were used. Controlling for demographic and disease associated variables, a series of hierarchical multiple regressions was run using neuropsychological tests scores and a measure of instrumental daily functioning as outcome (dependent) variables. An index of vascular burden was the predictor (independent) variable.
Results: Participants’ mean age and education were 69.72 (SD = 8.55) and 15.74 (SD = 3.7) years, respectively. 73.7% of the sample was male and 93.8% was White. While an index of vascular burden had statistically significant associations with a measure of functional activities and a test of word retrieval, it accounted for less than 2% of the variance in each. Regression analyses were not statistically significant for the remaining 8 neuropsychological measures.
Conclusion: No clinically significant association between vascular burden and either neuropsychological test performance or instrumental functioning was found.
Dennison, Kyle (2019). The Impact of Vascular Burden on Neuropsychological and Instrumental Daily Functioning in Parkinson’s Disease (Doctoral dissertation, Pacific University). Retrieved from:
Available for download on Saturday, November 20, 2021