Comparisons between hemodialysis (HD) and peritoneal dialysis (PD) have generally focused on differences in mortality between therapies. The present study was designed to examine patient (pt) satisfaction with HD and PD and pt perception of the impact of these therapies on quality of life (QOL). Also, it compared pt reported responses between HD and PD with respect to their impression of the most positive (+) and negative (-) aspects of their individual dialysis therapy (tx). Data was collected and analyzed with respect to individual pts' Charlson comorbidity indexes(CCls). 146 patients (62 PD, 84 HD) participated by filling out a committee-developed survey where 14 specific domains were queried about. These were developed from previous interviews concerning patients' perceptions of dialysis therapy on their life (Wuelth et al., Peritoneal Dialysis International 22: 184-190, 2002). These domains included stress, overall health, religion, social life (social, family, finances , religion, sex, living arrangements), self (mood, body image, appetite), and activity (independence, energy level, recreation, exercise ability). All questions were scored on a scale from 1-10, with the score of 1 indicating low satisfaction or negative impact and 10 indicating high satisfaction or positive impact. Pt free text responses to (+) and (-) aspects of dialysis were categorized into 12HD:10PD (+) categories and 19HD:22PD (-) categories, then further grouped into tx-based, symptom-based, and miscellaneous. Patient demographics indicated that HD patients were older than PD patients (69.6 yrs ± 13.3 vs. 55.0 yrs ± 13.7, p < 0.0001) and CCl were higher for HD vs PD (7.9 ± 1.87 vs 5.8 ± 2.68, P
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