Zinc is present in the metalloenzyme carbonic anhydrase which is found in the ciliary body and is involved in the production of aqueous humor. It is known that a reduction in carbonic anhydrase, via carbonic anhydrase inhibitors, lowers intraocular pressure. This paper investigates the possibility that chronic subnormal zinc nutriture may also decrease carbonic anhydrase activity and thus lower intraocular pressure. Ten subjects each having intraocular pressures < 10mm Hg, as measured by Goldmann tonometry, were selected from a normal clinical population. Ten control subjects, having intraocular pressures from 12-l?mm, were matched to the experimental group for sex and age. Hair zinc and other mineral levels were assessed for all subjects at the Parmae Laboratory in Dallas, Texas. Results indicate that there is no significant difference (at the .01 level) in hair zinc and other mineral levels for the experimental and control groups.
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