A clinical study of twenty-three subjects was conducted to compare corneal changes and patient responses observed with flat versus alignment fitting philosophies. Corneal changes were assessed by comparison of initial and endpoint data gathered on refractive status, corneal curvature, and corneal staining. The subjective response to lens comfort was also monitored. Corneas fitted with lenses on alignment showed statistically less change in corneal astigmatism, visual acuity, and staining than lenses fitted flat.
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