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Thesis

Visual cortical plasticity after the termination of the critical period: A review and experimental test

1 May 1995

Abstract

A literature review is presented in which stimulus deprivation amblyopia is discussed. Additionally, the review of literature covers aspects of attentional and motivational effects on stimulus deprivation amblyopia. Although the experimental design originally intended to induce amblyopia in six kittens born June 14, 1992, only two survived to become subjects in the study. The two kittens were monocularly deprived of light stimulation by wearing an opaque contact lens on the right eye during six hours of light exposure per day, five days per week, beginning at four weeks of age. At all other times, including the first four weeks of life, they were kept in the dark. Beginning at eleven weeks of age, the kittens were motivationally trained to recognize grating acuity patterns, and then acuity testing in the non-deprived eye began at twenty-two weeks of age. Reverse occlusion and acuity testing after the "critical period," for the purpose of exploring any motivational visual function recovery, began at thirty-seven weeks of age.


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