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A clinical evaluation of edge induced conjuctival staining with NewVues and SeeQuence disposable lenses

1 May 1991


Results from a previous study indicated that the Johnson & Johnson ACUVUE® disposable lens caused more conjunctival staining than the Bausch & Lomb SEEQUENCE™ lens.l The current study was performed in the same manner as the previous study to determine if the third type of disposable lens, the Ciba NewVues®, induced a significantly different amount of conjunctival staining from the Bausch & Lomb SEEQUENCE™ lens. Sixty subjects wore a SEEQUENCEn lens on one eye, and a NewVues lens on the other. Prior to dispensing the lenses, subjects were screened by two investigators to insure no conjunctival staining was present and that lens fits were acceptable. After 24 hours, a different investigator, who did not know which lens was worn on which eye, evaluated all subjects to determine the grade of conjunctival staining and the percentage of involvement for each quadrant. Weighted averages for each quadrant and lens type were computed from the grade and percentage of involvement. These weighted averages were used in a Wilcoxin signed-rank test to determine if there was a significant difference in conjunctival staining between lens types, and in a Friedman 4-way analysis to determine if any quadrants were significantly more affected than others. These analyses determined that the NewVues lens caused less conjunctival staining than the SEEQUENCE™ lens (p < 0.05) and that the inferior quadrant was more affected than other quadrants (p < 0.05).


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