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Depersonalization Disorder: A review of the literature

16 April 2004


Depersonalization disorder has only recently begun to be understood. Temporal lobe differences have been implicated in the disorder that make individuals feel like outside observers of their experiences, disconnected from their senses and surroundings. Depersonalization maybe the third most common psychiatric symptom; however, because only a few controlled or extensive studies investigating treatments have been conducted, researchers and practitioners have not agreed upon which strategy to carry out. Most individuals treated with psychotherapy report no significant decreases in depersonalization symptoms. Antidepressants, either alone or in conjunction with a benzodiazepine, are the most commonly prescribed and promising treatments. The tendency for depersonalization disorder to respond relatively poorly to all types of treatment warrants carefully conducted clinical trials.


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