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Prophylactic Use of Permethrin in Tick Infested Areas

11 August 2019


Background: The prevalence of tick-borne diseases in the U.S. continues to escalate causing a major public health concern. Due to challenges that providers are faced with when diagnosing and treating tick-borne diseases, such as Lyme Disease, preventative methods are critical. This is a systematic review on the EPA-approved use of permethrin-treated clothing and its efficacy in the reduction of tick bites.

Methods: An exhaustive medical literature review was conducted utilizing PubMed-MEDLINE, Web of Science, and CINAHL using keywords: permethrin and tick bites.

Results: The search produced 44 studies with 4 pertaining to the clinical question. One study was excluded, due to its completion in a clinical setting versus the outdoors. Two of three studies revealed a statistical difference between the treatment and control groups and were considered to be of moderate quality.

Conclusion: Statistically significant findings between groups, who wore permethrin-treated clothing, and those who did not, indicates that permethrin is an efficacious preventative method for tick bite reduction.

Keywords: Permethrin, permethrin-treated clothing, tick bites, vector-borne diseases, tick-borne diseases, Lyme Disease, Rocky Mountain Spotted Fever


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19 Mar 2020
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Main File
20 Mar 2020
406 kB