The edematous effects of P.M.M.A. contact lenses were compared with that produced by lenses made from Cellulose acetate butyrate (C.A.B .), a gas permeable material. Thirteen subjects were carefully selected who showed no contra-indications to contact lens wear other than the presence of corneal edema while wearing P.M.M.A. lenses. These subjects were observed while wearing both P.M.M.A. and C.A.B. (Meso) lenses. Pachometry was used to monitor changes in corneal thickness. Increased corneal thickness and visible edema were noted with P.M.M.A. lenses. C.A.B. lenses showed significantly less increase in corneal thickness and in most cases edema was reduced or completely eliminated for the duration of the study.
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