Corneal vascularization is a pathological process occurring in a cornea suffering physical and/or physiological insult. Its presentation could impair clear vision and thus its detection is important. Unfortunately current methods to detect and grade corneal vascularization are largely subjective and therefore a uniform system to identify and grade its presence does not exist. This study has explored a method using oral fluorescein angiography to examine corneal vessel growth. The results show that corneal vascularization fluoresces and leaks fluorescein during an oral fluorescein study. This information indicates that a method potentially exists to detect, grade and follow corneal vascularization through an objective means.
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