Accumulations of protein deposits on the surface of contact lenses are a major cause of problems associated with contact lens wear. Protein removal systems are part of a care regimen designed to remove protein deposits. This study compares the efficacy of Alcon® SupraClens® daily protein remover and Alcon® Opti-Free Express® multipurpose solution used in combination, Alcon® RGP Multipurpose Disinfecting Solution alone, and the combination of Alcon® RGP Multipurpose Disinfecting Solution and Alcon® SupraClens® daily protein remover. The solutions were tested using PMMA contact lenses and four different rigid gas permeable (RGP) contact lenses coated in vitro with a 0.01% lysozyme solution and stained with Coomassie Blue. The efficacy of protein removal relative to untreated lenses was analyzed by scanning densitometry. The results showed the combination of Alcon® SupraClens protein remover and Alcon® Opti-Free Express® multipurpose solution to be 34.6 to 63 .8% effective in removal oflysozyme from the RGP lenses. The combination of Alcon® RGP Multipurpose Disinfecting Solution and Alcon® SupraClens® daily protein remover was 46.9 to 70.4% effective in the removal of lysozyme. In contrast, Alcon® RGP Multipurpose Disinfecting Solution alone was, at best, 28.2% effective. All protein removal methods were only approximately 15% effective with the PMMA lenses. The results show SupraClens® is effective at removing in vitro coated lysozyme.
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